In the modern world there is a steady increase of scientific interest for the problems of state borders and border areas. This is due to trends of inter-civilizational and cross-cultural interaction, economic globalization, dramatic changes on the political map of the world, the democratization of information processes, and development of regional cooperation. Area studies emerged as a branch of science that studies, i.a., the spatial organization of the economy. The emerging new direction of cross-border regional studies is also focused on the economic issues of cross-border cooperation, which is new for the Russian regions. In the 1990s, the practice of these relations has evolved at a rapid pace leaving theoretical foundation and design within the framework of the scientific terminology behind. The border area, as part of the country, absorb the general tendencies of economic processes, and especially due to the peculiarity of geographical position. The same applies to socio-psychological processes. But if the economic potential, economics of frontier regions is reflected in the scientific literature, human potential, spiritual sphere, the state of the mass consciousness of various groups of the population are less studied, though, these factors are basic for social development. The article is devoted to the comparative analysis of the worldview, beliefs and attitudes of student youth of the Western and Eastern border regions of Russia.